*THIS IS A PART TIME ROLE, 20-25 HOURS A WEEK WITH FLEXIBLE HOURS.
Responsibilities :
• Maintain mammalian cell cultures that support in vitro disease modeling platforms, including iPSC human and animal cell lines.
• Conduct molecular and cell biology experiments to assess feasibility of retinal AAV gene therapies and small molecules, including digital PCR, protein quantitative assays, and novel and/or established in vitro functional assays.
• Accurately record, document, interpret experimental data, and present study results to multidisciplinary teams.
• Prepare and review protocols, laboratory documentation, inventory, technical reports, and standard operation procedures (SOPs).
• Independently work in a fast-paced and collaborative environment rich with opportunities for growth and training to expand skill sets.
Qualifications :
• A Bachelor’s or Master’s degree in Neuroscience, Ophthalmology, Pharmacology, Biology, Biomedical Engineering, or a related field.
• At least 4 years of hands-on experience with cell and molecular biology techniques such as cloning, ELISA, qPCR, digital PCR, and Western blotting.
• Preferred experience with viral vectors (AAV or Lenti-vectors) and iPSC line culture, maintenance, clone selection, and banking.
• Hands-on experience with cell culture (mammalian and iPSC cell lines) to design, create and maintain target-appropriate cell models for use in potency assays for multiple gene therapy programs. Experience with retinal cell models is preferred.
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